Hormone Replacement Therapy
at 24HR Pharmacy

Hormone Replacement Therapy (HRT) is used to replace the oestrogen (and sometimes progesterone) your body naturally makes less of around perimenopause and menopause. It helps relieve symptoms like:

Hot flushes and night sweats
Poor sleep, low mood, anxiety and "brain fog"
Vaginal dryness and discomfort during sex
Joint pains and loss of libido

See Treatment Options

Your Treatment Options

Utrogestan

Oestrogel

Elleste Solo

Elleste Duet Conti

Elleste Duet

Compare Your Options

For Hormone Replacement Therapy there are three key systemic treatment approaches as follows:

	Elleste Duet 1mg Tablets	Evorel Conti 50/170 Patches	Oestrogel 0.06% Gel + Utrogestan 100mg
What it is	Sequential combined HRT tablet containing estradiol (oestrogen) and norethisterone (progestogen). You take oestrogen-only tablets first, then combined tablets each cycle.	Continuous combined HRT patch with estradiol + norethisterone in one patch, releasing hormones steadily through the skin.	Transdermal estradiol gel (Oestrogel) applied to the skin, plus micronised "body-identical" progesterone (Utrogestan) capsules taken by mouth.
How it's taken/used	1 tablet daily – a course of oestrogen tablets for part of the month, followed by combined tablets for the rest, usually leading to a predictable monthly bleed.	1 patch worn at a time, changed twice weekly, giving both hormones every day with no tablet breaks. Designed for women whose periods have stopped for 12+ months.	Oestrogel is usually applied once daily (1–4 pumps depending on dose) to clean, dry skin; Utrogestan is taken on specific days each month (sequential) or daily (continuous) as directed, for womb protection.
Bleeding pattern	Regular withdrawal bleed once a month is expected (like a light period), especially in the early years after menopause.	Aims for no monthly bleed – suitable once you are postmenopausal; some spotting can occur initially.	Depends on regimen: can be sequential (monthly bleed) or continuous (no planned bleed) once you're further past menopause.
Who it may suit	Those who: are still relatively early post-menopause, prefer tablets, and don't mind a predictable monthly bleed.	Those who: are postmenopausal (≥12 months since last period), want no planned bleeding, and prefer patches (useful if you have migraine, higher clot risk, or don't tolerate tablets).	Those who: prefer a "body-identical" approach with transdermal oestrogen and micronised progesterone, wish to minimise clot risk (transdermal route) and may be sensitive to synthetic progestogens.
Pros	Simple once-daily tablet; combines both hormones in one pack; well-established option for many women.	Convenient twice-weekly patch change, steady hormone levels, avoids first-pass through the liver, and may have lower clot risk than oral HRT.	Flexible gel dosing; transdermal oestrogen (good for those with risk factors where patches/gels preferred); Utrogestan is body-identical progesterone, often better tolerated.
Key considerations	Not suitable if you cannot take oral combined HRT (e.g. certain clot/cancer histories). Needs regular review; small increase in breast cancer risk with longer-term combined HRT.	Must remember to change patches regularly and rotate sites; not suitable for everyone (e.g. some skin conditions, adhesive allergy).	Needs you to use two products correctly (gel + capsules); regime must be followed carefully to ensure womb lining is protected. Dose and schedule are individualised by your prescriber.

Your prescriber will decide which combination from your category (e.g. Elleste, Evorel, Oestrogel, Utrogestan, Premarin, vaginal estradiol) is safest and most effective for your specific situation.

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Who Is Eligible?

This service is designed for adults in the UK with menopausal symptoms who want to explore licensed HRT options via an online consultation.

You may be suitable if:

You're having bothersome perimenopausal or menopausal symptoms (e.g. hot flushes, night sweats, sleep disturbance, mood changes, vaginal dryness) affecting daily life
You're around the usual menopause age (often mid-40s to mid-50s), or have early menopause / premature ovarian insufficiency and been advised to take HRT until at least age ~51
You do not have a history of oestrogen-sensitive cancers and have no major untreated cardiovascular risk (like uncontrolled high blood pressure)
You're not pregnant or breastfeeding, and understand that HRT is not contraception – some people still need contraception until menopause is clearly reached

You may not be suitable for online-only HRT if:

You should usually get face-to-face specialist or GP advice instead if you:

Have ever had breast cancer, ovarian cancer or womb cancer, or are under active investigation for these
Have unexplained vaginal bleeding or thickening of the womb lining that hasn't been investigated
Have had a blood clot (DVT/PE), a stroke, heart attack or certain clotting conditions – particularly if considering oral HRT
Have severe liver disease, very high uncontrolled blood pressure, or complex cardiac disease
Are under 40 with suspected very early or complex menopause – these usually need a more detailed assessment
Are seeking gender-affirming hormone treatment – that requires a different specialist pathway

Seek urgent help immediately (A&E/999) if you develop:

Sudden chest pain or breathlessness
Painful swelling/redness in one calf
Sudden severe headache, weakness on one side, or trouble speaking

– whether or not you're on HRT.

Why choose 24 HR Pharmacy

Pharmacist-led: Every request is checked by a UK-registered prescriber against your medical history and current medicines.
Fast, discreet service: Simple online questionnaire, clear next steps, and discreet delivery to your door.
Ongoing support: Guidance on using your treatment safely, plus practical lifestyle tips to help you get results.
Transparent and responsible: We prescribe only when it is safe and appropriate, and we will suggest alternatives if a medicine is not right for you.

How Our Online Service Works?

Simple, safe, and designed around you. Here is what happens from start to finish.

Quick Online Consultation

You fill out a secure questionnaire covering:

Your age, periods and menopause stage (perimenopausal, periods stopped, surgical menopause, early menopause)
Your main symptoms (flushes, sleep, mood, joint pains, vaginal/urinary symptoms, etc.)
Past medical history – especially breast, ovarian or womb cancer, blood clots, stroke, heart disease, migraine with aura, liver disease, high blood pressure
Any previous HRT you've tried and how you got on with it
Medicines you take now (including anticoagulants, migraine drugs, epilepsy medicines, GLP-1 weight-loss injections, etc.)

This lets the prescriber match your symptoms and risk factors to a suitable type, route and dose of HRT – or advise on alternatives if HRT is not appropriate.

Reviewed by a UK Prescriber

A UK-registered prescriber will:

Confirm you're likely to be in perimenopause or menopause based on your symptoms and period history (most women do not need hormone blood tests)
Decide whether you need oestrogen-only HRT (if you've had a hysterectomy) or combined HRT (if you still have a womb)
Choose a suitable route: tablets, patches, gel with Utrogestan, or vaginal oestrogen tablets
Check for reasons not to use HRT, or to prefer transdermal rather than oral, such as: strong history of clots, migraine with aura, high BMI or certain other conditions

If HRT isn't suitable online, we won't supply it – instead you'll be signposted to your GP or menopause/secondary care services.

Fast, Discreet Dispensing & Delivery

If HRT is appropriate:

A private prescription is issued for the selected medicine(s)
Your medicine is dispensed from our UK-registered pharmacy in line with current UK guidance
Discreet parcels: No external product names on the box

You'll receive clear instructions on how and when to apply patches/gel or take tablets/capsules, and what to expect in terms of bleeding pattern.

2000+ Happy Customers

★★★★★

Hormone Replacement Therapyat 24HR Pharmacy